Fever blisters are caused by an initial infection with the herpes simplex virus (HSV-1). The main triggers of a fever blister outbreak can be due to external and internal causes.
| Internal factors | External factors |
|---|---|
| Fever | Windburn |
| Illness | Ultraviolet radiation (sunshine, tanning booths) |
| Menstruation | Chilling |
| Upset stomach or GI disturbance | Excitement |
| Minor infections | Emotional stress |
| Any disease that increases metabolism (e.g. diabetes, hyperthyroidism) | Drying of the lips |
| Presence of a second virus (e.g., common cold, flu) | Allergic reactions, including reactions to food |
| Fatigue | Any physical injury |
| Factors that depress the immune system | Dental treatment |
Herpatch helps to treat fever blisters throughout their entire cycle. Its effect goes even so far that the application of a Herpatch can help to prevent the occurrence of fever blisters, when the first tingling is felt on the lips!